Regierungsbezirk Kleve (or Cleves) was a Regierungsbezirk, or government region, of the Prussian Province of Jülich-Cleves-Berg.
The creation of the administrative region was decreed on April 30, 1815; it became active on 22 April 1816. Regierungsbezirk Kleve was incorporated into Regierungsbezirk Düsseldorf on 22 June 1822.
The Kleve region included the following districts: